The most important disadvantages of electrophoretic techniques are the health risks for operators, the pollution deriving from wastes, and the problem of repeatability of quantitative results. On the other hand, these analyzes require cheaper instruments and could be performed in almost all laboratories. By contrast, LC/MS is actually the most used technique in proteomic, it is highly accurate in quantitative and qualitative analysis and produce low levels of waste, but LC/MS systems are very expensive and require highly qualified operators.


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