Stem Cell Applications in Corneal Regeneration and Wound Repair
Steffi Matthyssen, Bert Van den Bogerd, Sorcha № Dhubhghaill, Carina Koppen, and Nadia Zakaria
Abbreviations
ABCG-2 ATP-binding cassette transporter subtype G-2
ACAID Anterior chamber-associated immune deviation
ALDH Aldehyde dehydrogenase
ALK Anterior lamellar keratoplasty
APC Antigen presenting cell
ATMP Advanced therapy medicinal product
ATP Adenosine triphosphate
CAOMECS Cultured autologous oral mucosal epithelial cell sheets
CK3 Cytokeratin 3
CK12 Cytokeratin 12
CLET Cultivated limbal epithelial transplant
S. Matthyssen • B. Van den Bogerd
Department of Ophthalmology, Visual Optics and Visual Rehabilitation, Faculty of Medicine and Health Sciences, Campus Drie Eiken, University of Antwerp, Wilrijk, Belgium e-mail: This email address is being protected from spam bots, you need Javascript enabled to view it
S. N Dhubhghaill • C. Koppen
Department of Ophthalmology, Visual Optics and Visual Rehabilitation, Faculty of Medicine and Health Sciences, Campus Drie Eiken, University of Antwerp, Wilrijk, Belgium
Department of Ophthalmology, Antwerp University Hospital, Edegem, Belgium
N. Zakaria (*)
Department of Ophthalmology, Visual Optics and Visual Rehabilitation, Faculty of Medicine and Health Sciences, Campus Drie Eiken, University of Antwerp, Wilrijk, Belgium
Department of Ophthalmology, Antwerp University Hospital, Edegem, Belgium
Center for Cell Therapy and Regenerative Medicine, Antwerp University Hospital, Edegem, Belgium © Springer International Publishing Switzerland 2017
P.V. Pham (ed.), Neurological Regeneration, Stem Cells in Clinical
Applications, DOI 10.1007/978-3-319-33720-3_13
DALK Deep anterior lamellar keratoplasty
DPC Dental pulp cell
DMEK Descemet’s membrane endothelial keratoplasty
DSAEK Descemet’s stripping automated endothelial keratoplasty
DSEK Descemet’s stripping endothelial keratoplasty
ECM Extracellular matrix
EDC 1-ethyl-3-(3-dimethyl aminopropyl) carbodiimide hydrochloride
EnMT Endothelial-to-mesenchymal transition
eTAC Early transient amplifying cell
FBS Fetal bovine serum
HAEC Human amniotic epithelial cells
HCEnC Human corneal endothelial cell
HCEnP Human corneal endothelial progenitor
hIDPSC Human immature dental pulp stem cell
HvGD Host-versus-graft disease
GAG Glycosaminoglycan
GvHD Graft-versus-host disease
IL Interleukin
iPSC Induced pluripotent stem cell
KLAL Keratolimbal allograft
LESC Limbal epithelial stem cell
LSCD Limbal stem cell deficiency
MHC I major histocompatibility complex I
MHC II major histocompatibility complex II
MMP Matrix metalloproteinase
MSC Mesenchymal stem cell
PG Proteoglycan
PK Penetrating keratoplasty
PMC Post-mitotic cell
PNIPAM Poly(N-isopropylacrylamide)
ROCK Rho-associated kinase
SP Side population
TAC Transient amplifying cell
TGF-pi Transforming growth factor-pi
Thi Type I helper T cell
Treg Regulatory T cells
TSG-6 Tumor necrosis factor-inducible gene 6 protein
TSP-1 Thrombspondin-1
VEGF Vascular endothelial growth factor
