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Home arrow Health arrow Cognitive impairment and dementia in Parkinson disease


The typical profile of PD-D is characterized by a dysexecutive syndrome with prominent impairment of attention, visuospatial function, memory, and frequent behavioural symptoms. Dementia in PD has an insidious onset and slow progression, and overt symptoms are usually preceded by more subtle changes. The annual rate of decline is similar to or somewhat less than that seen in AD. Old age, longer duration of disease, and a PIGD subtype are associated with higher risk and faster progression. The severity and topography of LB-type degeneration, as well as the presence and amount of coexisting pathologies, may determine the risk of developing dementia, time to onset, and the rate of progression.


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