Brief Review on Pharmacology and Biological Activity of Piper Species

Piper species have been reported to exhibit various pharmacological activities such as insecticidal, antibacterial, antiinflammatory, antiplatelet, anti hypertensive, hepatoprotective, antithyroid and antitumor activities (Iqbal et al. 2016; Khushbu et al. 2011; Kirtiker and Basu 2003; Yang et al. 2002; Ghoshal et al. 2002; Singh et al. 2009; Scott et al. 2008; Kaou et al. 2008; Karsha and Bhagya Lakshmi 2010; Vaghasiya et al. 2007; Tsai et al. 2005; Munshi and Ljungkvist 1972) (Table 1.2).

Insecticidal and Acaricidal Activity

Pipernonaline and piperoctadecalidine, the two alkaloids present in the essential oil of P. longum, exhibited insecticidal and insect-repellant activities against five species of arthropod pests (Kokate et al. 1980; Park et al. 2002).

Antifungal Activity

Essential oil of P. longum possesses broad-spectrum antifungal activity. In an in vivo study fruit, essential oil exhibited excellent antifungal activity against Botrytis cineria, Erysiphe graminis, Pyricularia oryzae,

S. NO.

SPECIES

PART USED

ACTIVITY

REFERENCE

1.

P longum

Essential oil

Insecticidal and insect-repellant

Kokate et al. 1980; Jeong et al. 2002

2.

P. longum

Ethanolic extract

antiulcer

Agrawal et al. 2000

3.

P. nigrum

Ethanolic extract

Gastric emptying inhibitory

Bajad et al. 2001 b

4.

P. longum

Ethanolic extract

Bioavailability enhancers

Atal et al. 1981

5.

P. longum

Ethanolic extract

Antisnake venom

Shenoy et al. 2013

6.

P longum

Alcoholic extract of fruit

Anti platelet

Das et al. 1998

7.

P. longum

Fruit extract

Coronary vasodilation

Shoji et al. 1986

8.

P. longum

Essential oil

Antifungal

Lee et al. 2001

9.

P. longum

Methanolic extract of fruit

Antiamoebic

Ghoshal et al. 2002; Ghoshal et al. 1996; Sawangjaroen et al. 2004

10.

Piper species

Ethanolic extract of fruit

Adulticidal

Choochote et al. 2006

11.

Piper species

Ethanolic extract of fruit

Anti obesity

Lee et al. 2005

12.

Piper species

Ethanolic extract of fruit

Larvicidal

Chaithong et al. 2006; Yang et al. 2002

13.

Piper species

Ethanolic extract of fruit

Antidepressant

Seon et al. 2005; Song et al. 2007; Lee et al. 2008

14.

Piper species

Alcoholic extract of fruit

Anticancer and Antitumor

Anuradha et al. 2004; Pradeep et al. 2002; Bezerra et al. 2006

('Continued)

5. NO.

SPECIES

PART USED

ACTIVITY

REFERENCE

15.

Piper species

Alcoholic extract of fruit

Anti asthmatic

Kulshresta et al. 1969; Kulshresta et al. 1971

16.

Piper species

Aqueous extract of fruit

Antidiabetic

Nabi et al. 2013; Manoharan et al. 2007

17.

Piper species

Alcoholic extract of fruit

Hypocholesterolemic

Wang et al. 1993; Wu and Bao 1992

18.

Piper species

Alcoholic extract of fruit

Hepatoprotective

Koul and Kapil 1993; Christina et al. 2006

19.

Piper species

Aqueous extract of root

Analgesic

Vedhanayaki et al. 2003

20.

Piper species

Alcoholic extract of fruit

Antiapoptotic

Yadav et al. 2014; Natarajan et al. 2006

21.

Piper species

Ethanolic extract of fruit

Antiinflammatory

Kumar et al. 2005; Choudhary 2006; Stohr etal. 2001

22.

Piper species

Ethanolic extract of fruit

Immunomodulatory

Mananvalan and Singh 1979

23.

Piper species

Aqueous extract of fruit

Antiarthritic

Yende et al. 2010

24.

Piper species

Methanolic extract of fruit

Protective myocardial

Mishra 2010

25.

Piper species

Root

Antifertility

Lakshmi et al. 2006; Garg 1981; Munshi et al. 1972; Munshi et al. 1972

26.

Piper species

Ethanolic extract of fruit

Radioprotective

Sunila and Kuttan 2004

Phytophthora infestans, Puccinia recondita and Rhizoctonia solani (Lee et al. 2001; Ghoshal et al. 2002; Ghoshal et al. 1996). Pipernonaline (alkaloid) isolated from the hexane fraction of P. longum was found potent against P. recondita (Sawangjaroen et al. 2004). P. longum extracts exhibited good antifungal activity against Aspergillus niger (Ab Rahman et al. 2014).

 
Source
< Prev   CONTENTS   Source   Next >