Patent Studies in Omics Approaches for the Detection of Food Adulterants

Some of the list of patents filed using omics approaches to detect the adulterants present in a given food are mentioned below (Table 1).

Table 1. Patent studies in omics approaches for the detection of food adulterants.

Table 1 contd....

...Table 1 contd.

Conclusion and Future Opportunities

From the above study it can be concluded that omics-based technology is hugely contributing to the identification of food adulterants. These adulterants are compromising the health of human beings globally. A gap in demand and supply chain has also led to a rise the use of adulterants. Root-level eradication of availability of adulterants is required. Stringent monitoring and some basic knowledge to consumers might play an important role. Further development of new technologies, which can identify in a lesser time and are user friendly, is required.

Acknowledgments

Authors are grateful to the Director, Indian Institute of Information Technology Una, Himachal Pradesh for providing the necessary facility to pursue the present work.

References

Abusaloua, A., Mohamed, G., Ali, E.A. and Zahmol, E.W. (2019). Food additives and preservatives as slow poisons. Scientific Journal of Applied Sciences of Sabratha University 3(3): 42-48.

Agrawal, G.K., Jwa, N.S. and Rakwal, R. (2009). Rice proteomics: Ending phase I and the beginning of phase II. Proteomics 9(4): 935-963.

Agrimonti, C. and Marmiroli, N. (2018). Genomics for detecting adulteration in dairy food chain. Adulteration Analysis of Some Foods and Drugs 1(24): 13-36.

Al-Mohanna, T, Ahsan, N., Bokros, N.T., Dimlioglu, G., Reddy, K.R., Shankle, M., Popescu, G.V. and Popescu, S.C. (2019). Proteomics and proteogenomics analysis of sweet potato (Ipomoea batatas) leaf and root. Journal of Proteome Research 18(7): 2719-2734.

Amin, A.M., Avik, S.R., Ahsan, S. and Khan, I.H. (2004). Eating away our health. Star Weekend Magazine The Daily Star, 8-13.

Arif, A.M., Javed, I., Ayaz, M., Abdullah, M., Imran, M., Rashid, A., Shahbaz, Gondal, T., Qaisarani, T.B., Iqbal, Z., Salehi, B., Sharifi-Rad, J. and Martorel, M. (2020). Chemical composition, adulteration, total microbial load, and heavy metal in raw milk samples collected from dairy farms and urban areas in Lahore district. Pakistan Journal of Food Safety 40(1): el2729.

Atooh, C.A. and Sowley, E.N. (2018). Effect of heavy metals in brewery water sources and pito brewed from them in tamale metropolis and Tolon district, Ghana. Journal of Scientific Research and Reports 19(5): 1-10.

Au, A., Cheng, K.K. and Wei, L.K. (2016). Metabolomics, lipidomics and pharmacometabolomics of human hypertension. Hypertension: From Basic Research to Clinical Practice 956: 599-613.

Azad, T. and Ahmed, S. (2016). Common milk adulteration and their detection techniques. International Journal of Food Contamination 3(1): 22-31.

Balint, A., Kiss, R., Szaniszlo, A. and Bayoumi-Hamuda, H.E.A.F. (2018). The effect of heavy metals to be found in the environment on the human body. Proceedings of ECOpole 12(1): 11-20.

Ballin, N.Z. and Laursen, K.H. (2019). To target or not to target? Definitions and nomenclature for targeted versus non-targeted analytical food authentication. Trends in Food Science & Technology 86: 537-543.

Bartelt-Hunt, S., Snow, D.D., Damon-Powell, T. and Miesbach, D. (2011). Occurrence of steroid hormones and antibiotics in shallow groundwater impacted by livestock waste control facilities. Journal of Contaminant Hydrology 123(3-4): 94-103.

Basile, F., Beverly, M.B., Voorhees, K.J. and Hadfield, T.L. (1998). Pathogenic bacteria: Their detection and differentiation by rapid lipid profiling with pyrolysis mass spectrometry. TrAC Trends in Analytical Chemistry 17(2): 95-109.

Billah, W. (2007). Kaporer Lai Ronge Lai Chal, (Red Rice with Red Textile Dye). The Daily Prothom Alo, 3.

Bohme, K., Calo-Mata, P., Barros-Velazquez, J. and Ortea, I. (2019). Review of recent DNA- based methods for main food-authentication topics. Journal of Agricultural and Food Chemistry 67(14): 3854-3864.

Brasil, B.D.S.A.F., Gonsalves, D.M., Figueiredo, R.D.S.A. and Oliveira, D.A. A.D. (2013). Method and kit for quantifying material of bovine and bubaline origin in products of animal origin, WO. Patent No2013177639Al, Geneva, Switzerland, World Intellectual Property Organization International Bureau.

Burnum-Johnson, K.E., Kyle, J.E., Eisfeld, A.J., Casey, C.P., Stratton, K.G., Gonzalez, J.F. and Thackray, L.B. (2017). MPLEx: A method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling. Analyst 142(3): 442-448.

Byrd-Bredbenner, C, Cohn, M.N., Farber, J.M., Harris, L.J., Roberts, T, Salin, V., Singh, M., Jaferi, A. and Sperber, W.H. (2015). Food safety considerations for innovative nutrition solutions. Annals of the New York Academy of Sciences 1347(1): 29-44.

Cajka, T. and Fiehn, O. (2016). Toward merging untargeted and targeted methods in mass spectrometry-based metabolomics and lipidomics. Analytical Chemistry 88(1): 524-545.

Carvalho, F.P. (2017). Pesticides, environment, and food safety. Food and Energy Security 6(2): 48-60.

Celik, S.E., Asfoor, A., $enol, O. and Apak, R. (2019). Screening method for argan oil adulteration with vegetable oils: An online hplc assay with postcolumn detection utilizing chemometric multidata analysis. Journal of Agricultural and Food Chemistry 67(29): 8279-8289.

Chawla, R., Arora, J.S., Dubey, R.K. and Mukhopadhyay, C.S. (2018). Omics approaches and applications in dairy and food processing technology, pp. 271-295. In: Omics Technologies and Bio-Engineering, Academic Press.

Cheng, D„ Ngo, H.H., Guo, W„ Chang, S.W., Nguyen, D.D., Liu, Y„ Wei, Q. and Wei, D. (2019). A critical review on antibiotics and hormones in swine wastewater: Water pollution problems and control approaches. Journal of Hazardous Materials, 121-682.

Cho, J., Lee,J., Lim, C.U. and Ahn, J. (2016). Quantification of pesticides in food crops using QuEChERS approaches and GC-MS/MS. Food Additives & Contaminants: Part A 33(12): 1803-1816.

Cutarelli, A., Amoroso, M.G., De Roma, A., Girardi, S., Galiero, G., Guarino, A. and Corrado, F. (2014). Italian market fish species identification and commercial frauds revealing by DNA sequencing. Food Control 37:46-50.

Danezis, G.P., Tsagkaris, A.S., Camin, F., Brusic, V. and Georgiou, C.A. (2016). Food authentication: Techniques, trends & emerging approaches. TrAC Trends in Analytical Chemistry 85: 123-132.

Dasenaki, M.E., Drakopoulou, S.K., Aalizadeh, R. and Thomaidis, N.S. (2019). Targeted and untargeted metabolomics as an enhanced tool for the detection of pomegranate juice adulteration. Foods 8(6): 212.

Delwiche, S.R. (2016). Advances in the identification of adulterated cereals and cereal products, pp. 491-518. lit: Advances in Food Authenticity Testing, Woodhead Publishing.

Den Bakker, H.C., Allard, M.W., Bopp, D., Brown, E.W., Fontana, J., Iqbal, Z., Kinney, A., Limberger, R., Musser, K.A., Shudt, M. and Strain, E. (2014). Rapid whole-genome sequencing for surveillance of Salmonella enterica serovar enteritidis. Emerging Infectious Diseases 20(8): 1306.

Deng, X., den Bakker, H.C. and Hendriksen, R.S. (2016). Genomic epidemiology: Whole genome-sequencing-powered surveillance and outbreak investigation of food-borne bacterial pathogens. Annual Review of Food Science and Technology 7: 353-374.

Dickey, S.W., Cheung, G.Y. and Otto, M. (2017). Different drugs for bad bugs: Anti-virulence strategies in the age of antibiotic resistance. Nature Reviews Drug Discovery 16(7): 457.

Donne, G.C., Laudet, V. and Hanni, C. (2004). Method for detecting material from gadiform fish, useful for detecting adulteration of foods, based on amplification of mitochondrial DNA; also new oligonucleotides and amplicons. France Patent No. FR2858631A1.

Dubois-Brissonnet, F., Trotier, E. and Briandet, R. (2016). The biofilm lifestyle involves an increase in bacterial membrane saturated fatty acids. Frontiers in Microbiology 7:1673.

Dunn, W.B. and Ellis, D.I. (2005). Metabolomics: Current analytical platforms and methodologies. TrAC Trends in Analytical Chemistry 24(4): 285-294.

Dupuis, A., Hennekinne, J.A., Garin, J. and Brun, V. (2008). Protein Standard Absolute Quantification (PSAQ) for improved investigation of staphylococcal food poisoning outbreaks. Proteomics 8(22): 4633-4636.

Ellis, D.I., Dunn, W.B., Griffin, J.L., Allwood, J.W. and Goodacre, R. (2007). Metabolic Fingerprinting as a Diagnostic Tool, 1243-1266.

Ellis, D.I., Brewster, V.L., Dunn, W.B., Allwood, J.W., Golovanov, A.P. and Goodacre, R. (2012). Fingerprinting food: Current technologies for the detection of food adulteration and contamination. Chemical Society Reviews 41(17): 5706-5727.

Ellis, D.I., Muhamadali, H., Allen, D.P., Elliott, C.T. and Goodacre, R. (2016). A flavour of omics approaches for the detection of food fraud. Current Opinion in Food Science 10: 7-15.

Elsaman, R., Ali, G.A.M., Uosif, M.A.M., El-Taher, A. and Chong, K.F. (2020). Transfer factor of natural radionuclides from clay loam soil to sesame and cowpea: radiological hazards. International Journal of Radiation Research 18(1): 157-166.

Esimbekova, E.N., Asanova, A.A., Deeva, A.A. and Kratasyuk, V.A. (2017). Inhibition effect of food preservatives on endoproteinases. Food Chemistry 235: 294-297.

Faour-Klingbeil, D. and Todd, E. (2020). Prevention and control of food-borne diseases in middle-east and north African countries: Review of national control systems. International Journal of Environmental Research and Public Health 17(1): 70.

Fatma, F., Kamal, A. and Srivastava, A. (2018). Exogenous application of salicylic acid mitigates the toxic effect of pesticides in Vigita radiata (L.) Wilczek. Journal of Plant Growth Regulation 37(4): 1185-1194.

Fiehn, O. (2002). Metabolomics—The link between genotypes and phenotypes, pp. 155-171. In: Functional Genomics, Springer, Dordrecht.

Galimberti, A., De Mattia, F., Losa, A., Bruni, I., Federici, S., Casiraghi, M., Martellos, S. and Labra, M. (2013). DNA barcoding as a new tool for food traceability. Food Research International 50(1): 55-63.

Garcia-Canas, V., Simo, C., Herrero, M., Ibanez, E. and Cifuentes, A. (2012). Present and future challenges in food analysis: Foodomics. Analytical Chemistry 84(23): 10150-10159.

Gaso-Sokac, D., Kovac, S. and Josic, D. (2010). Application of proteomics in food technology and food biotechnology: Process development, quality control and product safety. Food Technology & Biotechnology 48(3): 284-295.

Gauglitz, J.M., Aceves, C.M., Aksenov, A.A., Aleti, G., Almaliti, J., Bouslimani, A., Caraballo- Rodriguez, A.M., Chaar, R. and da Silva, R.R. (2020). Untargeted mass spectrometry- based metabolomics approach unveils molecular changes in raw and processed foods and beverages. Food Chemistry 302:125-290.

German, J.B., Gillies, L.A., Smilowitz, J.T., Zivkovic, A.M. and Watkins, S.M. (2007). Lipidomics and lipid profiling in metabolomics. Current Opinion in Lipidology 18(1): 66-71.

Gharibzahedi, S.M.T. and Jafari, S.M. (2017). The importance of minerals in human nutrition: Bioavailability, food fortification, processing effects and nanoencapsulation. Trends in Food Science & Technology 62: 119-132.

Giacometti, J., Tomljanovic, A.B. and Josic, D. (2013). Application of proteomics and metabolomics for investigation of food toxins. Food Research International 54(1): 1042-1051.

Gomiero, T. (2018). Food quality assessment in organic vs. conventional agricultural produce: findings and issues. Applied Soil Ecology 123: 714-728.

Gonsalves, J.L., Figueira, J.A., Rodrigues, F.P., Ornelas, L.P., Branco, R.N., Silva, C.L. and Camara, J.S. (2014). A powerful methodological approach combining head space solid phase microextraction, mass spectrometry and multivariate analysis for profiling the volatile metabolomic pattern of beer starting raw materials. Food Chemistry 160:266-280.

Gore, J.P., Singh, R., Tay, A. and Santhanakrishnan, S. (2003). Method for measuring the amount of an organic substance in a food product with infrared electromagnetic radiation, U.S. Patent No. 7288768B2, Washington, DC: U.S. Patent and Trademark Office.

Grace, D. (2015). Food safety in low and middle income countries. International Journal of Environmental Research and Public Health 12(9): 10490-10507.

Gupta, S. and Gupta, K. (2020). Bioaccumulation of pesticides and its impact on biological systems. Pesticides in Crop Production: Physiological and Biochemical Action, 55-67.

Havlik, P.Z., Abhari, R., Roth, E.G. and Tomlinson, H.L. (2013). Method of processing adulterated biomass feedstock, U.S. Patent No. 6,885,550, Washington, DC: U.S. Patent and Trademark Office.

Hembrom, S., Singh, B., Gupta, S.K. and Nema, A.K. (2020). A comprehensive evaluation of heavy metal contamination in foodstuff and associated human health risk: a global perspective, pp. 33-63. In: Contemporary Environmental Issues and Challenges in Era of Climate Change, Springer, Singapore.

Hoffmann, V., Moser, C. and Saak, A. (2019). Food safety in low- and middle-income countries: The evidence through an economic lens. World Development 123:104611.

Hossain, M.M., Heinonen, V. and Islam, K.Z. (2008). Consumption of foods and foodstuffs processed with hazardous chemicals: A case study of Bangladesh. International Journal of Consumer Studies 32(6): 588-595.

Hrncirova, L., Hudcovic, T., Sukova, E., Machova, V., Trckova, E., Krejsek, J. and Hrncir, T. (2019). Human gut microbes are susceptible to antimicrobial food additives in vitro. Folia Microbiologica 64(4): 497-508.

Hyotylainen, T., Bondia-Pons, I. and Oresic, M. (2013). Lipidomics in nutrition and food research. Molecular Nutrition & Food Research 57(8): 1306-1318.

India Today (October 2018). Common Food Adulterants in India.

Inoue, K., Tanada, C, Sakamoto, T., Tsutsui, H., Akiba, T., Min, J.Z., Todoroki, K., Yamano, Y. and Toyooka, T. (2015). Metabolomics approach of infant formula for the evaluation of contamination and degradation using hydrophilic interaction liquid chromatography coupled with mass spectrometry. Food Chemistry 181: 318-324.

Islam, M.S., Ahmed, M.K. and Habibullah-al-Mamun, M. (2014). Heavy metals in cereals and pulses: Health implications in Bangladesh. Journal of Agricultural and Food Chemistry 62(44): 10828-10835.

Jain, M., Petzold, C.J., Schelle, M.W., Leavell, M.D., Mougous, J.D., Bertozzi, C.R., Leary, J.A. and Cox, J.S. (2007). Lipidomics reveals control of Mycobacterium tuberculosis virulence lipids via metabolic coupling. Proceedings of the National Academy of Sciences 104(12): 5133-5138.

Joshi, K. and Patil, D. (2017). Proteomics. Innovative Approaches in Drug Discovery, 273-294. doi:10.1016/b978-0-12-801814-9.00009-x.

Kai, W., Qiangqiang, L., Liming, W. and Xiaofeng, X. (2017). Method for rapidly analyzing lipid components in bee pollen. China Patent No. 107389847 B, Beijing, China, Liheng Liye Patent Agency Office.

Kalpana, S., Priyadarshini, S.R., Leena, M.M., Moses, J.A. and Anandharamakrishnan, C. (2019). Intelligent packaging: Trends and applications in food systems. Trends in Food Science & Technology 93:145-157.

Kaur, R. and Goyal, D. (2019). Toxicity and degradation of the insecticide monocrotophos. Environmental Chemistry Letters, 1-26.

Khoshnoud, M.J., Siavashpour, A., Bakhshizadeh, M. and Rashedinia, M. (2018). Effects of sodium benzoate, a commonly used food preservative, on learning, memory, and oxidative stress in brain of mice. Journal of Biochemical and Molecular Toxicology 32(2): e22022.

Kim, D.G., Lee, S.H., Cho, B.K., Byeon, D.H., Lee, J. and Lee, W.H. (2020). Statistical analysis for determining optimal sample size for living modified organism (LMO) seed detection. Journal of Crop Science and Biotechnology 23(1): 1-7.

Kim, H., Hong, Y., Park, J.E., Sharma, V.K. and Cho, S.I. (2013). Sulfonamides and tetracyclines in livestock wastewater. Chemosphere 91(7): 888-894.

Korte, R. and Brockmeyer, J. (2017). Novel mass spectrometry approaches in food proteomics. TrAC Trends in Analytical Chemistry 96: 99-106.

Kumar, R., Kharya, P. and Jain, P.K. (2019). Your daily life covered with harmful chemicals: A review on food adulteration. Progressive Agriculture 19(2): 262-265.

Larance, M. and Lamond, A.I. (2015). Multidimensional proteomics for cell biology. Nature Reviews Molecular Cell Biology 16(5): 269-280.

Lee, S.I., Kim, S.A., Park, S.H. and Ricke, S.C. (2019). Molecular and new-generation techniques for rapid detection of food-borne pathogens and characterization of microbial communities in poultry meat. pp. 235-260. In: Food Safety in Poultry Meat Production, Springer, Cham.

Lee, Y.H., Goh, W.W.B., Ng, C.K., Raida, M„ Wong, L„ Lin, Q„ Boelsterli, U.A. and Chung, M.C. (2013). Integrative toxicoproteomics implicates impaired mitochondrial glutathione import as an off-target effect of troglitazone. Journal of Proteome Research 12(6): 2933-2945.

Li, M., Yang, L., Bai, Y. and Liu, M. (2014). Analytical methods in lipidomics and their applications. Analytical Chemistry 86(1): 161-175.

Linke, B.G., Casagrande, T.A. and Cardoso, L.A. (2018). Food additives and their health effects: A review on preservative sodium benzoate. African Journal of Biotechnology 17(10): 306-310.

Lisa, M. and Holcapek, M. (2015). High-throughput and comprehensive lipidomic analysis using ultrahigh-performance supercritical fluid chromatography-mass spectrometry. Analytical Chemistry 87(14): 7187-7195.

Lockhart, D.J., Dong, H., Byrne, M.C., Follettie, M.T., Gallo, M.V., Chee, M.S., Mittmann, M., Wang, C, Kobayashi, M., Norton, H. and Brown, E.L. (1996). Expression monitoring by hybridization to high-density oligonucleotide arrays. Nature Biotechnology 14(13): 1675-1680.

Lopez-Ruiz, R., Romero-Gonzalez, R. and Frenich, A.G. (2019). Metabolomics approaches for the determination of multiple contaminants in food. Current Opinion in Food Science 28:49-57.

Lu, Z., Babajanian, S., Zhang, Y., Chang, P., Swanson, G. and Rubinsky, M. (2018). Authentication of botanical DNA isolated from dietary supplements, U.S. Patent No. 20190032153A1, Washington, DC: U.S. Patent and Trademark Office.

Mahmood, I., Imadi, S.R., Shazadi, K., Gul, A. and Hakeem, K.R. (2016). Effects of pesticides on environment, pp. 253-269. hi: Plant, Soil and Microbes, Springer, Cham.

Martinovic, T., Andjelkovic, U., Gajdosik, M.S., Resetar, D. and Josic, D. (2016). Food-borne pathogens and their toxins. Journal of Proteomics 147: 226-235.

Mendez, E., Gonzalez-Fuentes, M.A., Rebollar-Perez, G., Mendez-Albores, A. and Torres, E. (2017). Emerging pollutant treatments in wastewater: Cases of antibiotics and hormones. Journal of Environmental Science and Health, Part A 52(3): 235-253.

Mirza, S.K., Asema, U.K. and Kasim, S.S. (2017). To study the harmful effects of food preservatives on human health. Journal of Medicinal Chemistry and Drug Discovery 2: 610-616.

Mohammad, A.M., Chowdhury, T, Biswas, B. and Absar, N. (2018). Food poisoning and intoxication: A global leading concern for human health, pp. 307-352. In: Food Safety and Preservation, Academic Press.

Mohammadzadeh-Aghdash, H., Akbari, N., Esazadeh, K. and Dolatabadi, J.E.N. (2019). Molecular and technical aspects on the interaction of serum albumin with multifunctional food preservatives. Food Chemistry 293:491-498.

Murphy, S.A. and Nicolaou, A. (2013). Lipidomics applications in health, disease and nutrition research. Molecular Nutrition & Food Research 57(8): 1336-1346.

Nocella, G., Romano, D. and Stefani, G. (2014). Consumers' attitudes, trust and willingness to pay for food information. International Journal of Consumer Studies 38(2): 153-165.

Pang, Y., Zang, X., Li, H., Liu,)., Chang, Q., Zhang, S., Wang, C. and Wang, Z. (2020). Solid-phase microextraction of organophosphorous pesticides from food samples with a nitrogen- doped porous carbon derived from g-C3N4 templated MOF as the fiber coating. Journal of Hazardous Materials 384: 121430.

Patel, A. (2015). Kit to detect milk adulteration, W.O. Patent No.2015/132648A2, Geneva, Switzerland. World Intellectual Property Organization International Bureau.

Patti, G.J., Yanes, O. and Siuzdak, G. (2012). Metabolomics: the apogee of the omics trilogy. Nature Reviews Molecular Cell Biology 13(4): 263-269.

Pereira, L.H., Hanner, R., Foresti, F. and Oliveira, C. (2013). Can DNA barcoding accurately discriminate megadiverse neotropical freshwater fish fauna? BMC Genetics 14(1): 20.

Pimentel, G., Burton, K.J., Vergeres, G. and Dupont, D. (2018). The role of foodomics to understand the digestion/bioactivity relationship of food. Current Opinion in Food Science 22: 67-73.

Pintu, F.R. (2015). Metabolomics—The new frontier in food safety and quality research. Food Research International 72: 80-81.

Prakash, B., Singh, P.P., Kumar, A. and Gupta, V. (2020). Prospects of omics technologies and bioinformatics approaches in food science, pp. 317-340. hr. Functional and Preservative Properties of Phytochemicals, Academic Press.

Qiang, M, Xianshuang, M., Wentao, L., Wenfeng, Y. and Birch, W. (2020). Rapid detection of rhodamine В and watermelon in hot pot bottom Clopiuron method. China patent No. CN 110646498, Beijing, China, Liheng Liye Patent Agency Office.

Rashid, S. (2007a). Vejale Chheye Gechhe Desh (The Country has been Flooded with Adulterated Foods). The daily Janakantha, pp. 1 and 11, Bangladesh.

Rashid, S. (2007b). Sorbotro Sorbonasa Formaline (Everywhere, the Dangerous Formalin), The daily Janakantha, pp. 1-2, Bangladesh.

Redan, B.W., Jablonski, J.E., Halverson, C, Jaganathan, Mabud, M.A. and Jackson, L.S. (2019). Factors affecting transfer of the heavy metals arsenic, lead, and cadmium from diatomaceous-earth filter aids to alcoholic beverages during laboratory-scale filtration. Journal of Agricultural and Food Chemistry 67(9): 2670-2678.

Reeves, W.R., McGuire, M.K., Stokes, M. and Vicini, J.L. (2019). Assessing the safety of pesticides in food: How current regulations protect human health. Advances in Nutrition 10(1): 80-88.

Remington, B.C., Baumert, J.L., Blom, W.M., Houben, G.F., Taylor, S.L. and Kruizinga, A.G. (2015). Unintended allergens in precautionary labeled and unlabeled products pose significant risks to UK allergic consumers. Allergy 70(7): 813-819.

Ren, Y., Li, X., Liu, Y., Yang, L., Cai, Y., Quan, S., Pan, L. and Chen, S. (2017). A novel quantitative real-time PCR method for identification and quantification of mammalian and poultry species in foods. Food Control 76:42-51.

Rolim, A.E.H., Henrique-Araujo, R., Ferraz, E.G., Dultra, F.K.D.A.A. and Fernandez, L.G. (2015). Lipidomics in the study of lipid metabolism: Current perspectives in the omic sciences. Gene 554(2): 131-139.

Rolle, C, Lin, Z. and Healey, S. (2017). Computational approaches on photon-attenuation and coincidence-summing corrections for the detection of gamma-emitting radionuclides in foods. Applied Radiation and Isotopes 126: 134-137.

Ronquillo, M.G. and Hernandez, J.C.A. (2017). Antibiotic and synthetic growth promoters in animal diets: Review of impact and analytical methods. Food Control 72: 255-267.

Rosculete, E., Olaru, A.L., Rosculete, C.A. and Bonciu, E. (2019). Assessment of cytological effects of food preservative potassium metabisulphite to Allium сера. American Journal of Plant Sciences 11(1): 11-23.

Samavat, H., Seaward, M.R.D., Aghamiri, S.M.R. and Reza-Nejad, F. (2006). Radionuclide concentrations in the diet of residents in a high level natural radiation area in Iran. Radiation and Environmental Biophysics 45(4): 301-306.

Sapbamrer, R. and Hongsibsong, S. (2019). Effects of prenatal and postnatal exposure to organophosphate pesticides on child neurodevelopment in different age groups: A systematic review. Environmental Science and Pollution Research 26(18): 18267-18290.

Schirle, M., Bantscheff, M. and Kuster, B. (2012). Mass spectrometry-based proteomics in preclinical drug discovery. Chemistry & Biology 19(1): 72-84.

Senizza, B., Rocchetti, G., Ghisoni, S., Busconi, M., Pascual, M.D.L.M., Fernandez, J.A., Lucini, L. and Trevisan, M. (2019). Identification of phenolic markers for saffron authenticity and origin: An untargeted metabolomics approach. Food Research International 126:108584.

Shanthi, G., Kumaran, J.T.T., Raj, G.A.G. and Maniyan, C.G. (2010). Natural radionuclides in the South Indian foods and their annual dose. Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment 619(1-3): 436-440.

Shehata, H.R., Naaum, A.M., Garduno, R.A. and Hanner, R. (2018). DNA barcoding as a regulatory tool for seafood authentication in Canada. Food Control 92: 147-153.

Shepherd, L.V., Fraser, P. and Stewart, D. (2011). Metabolomics: A second-generation platform for crop and food analysis. Bioanalysis 3(10): 1143-1159.

Shigeoka, Y., Myose, H., Akiyama, S., Matsumoto, A., Hirakawa, N., Ohashi, H., Higuchi, K. and Arakawa, H. (2019). Temporal variation of radionuclide contamination of marine plants on the Fukushima coast after the East Japan nuclear disaster. Environmental Science & Technology 53(16): 9370-9377.

Sibbald, M.J.J.B., Ziebandt, A.K., Engelmann, S., Hecker, M., De Jong, A., Flarmsen, H.J.M., Raangs, G.C., Stokroos, I., Arends, J.P., Dubois, J.Y.F. and Van Dijl, J.M. (2006). Mapping the pathways to staphylococcal pathogenesis by comparative secretomics. Microbiology and Molecular Biology Reviews 70(3): 755-788.

Tagliavia, M., Nicosia, A., Salamone, M., Biondo, G., Bennici, C.D., Mazzola, S. and Cuttitta, A. (2016). Development of a fast DNA extraction method for seafood and marine species identification. Food Chemistry 203: 375-378.

Tang, S., Orsi, R.H., Luo, H., Ge, C, Zhang, G., Baker, R.C., Stevenson, A. and Wiedmann, M. (2019). Assessment and comparison of molecular subtyping and characterization methods for Salmonella. Frontiers in Microbiology 10: 1591.

The daily Prothom Alo. (2005). Chemical die Aam Pakanor Ovijoge Chhoijoner Saja (Six were Punished for Ripening Mango Using Chemicals), Bangladesh, pp. 19-20.

Titz, B., Elamin, A., Martin, E, Schneider, T., Dijon, S., Ivanov', N.V. and Peitsch, M.C. (2014). Proteomics for systems toxicology. Computational and Structural Biotechnology Journal 11(18): 73-90.

Toth, A.D. and Tselios, M. (2012). Device, method, system and kit for the detection of contaminants and/or pathogens in consumables by way of a color-change analysis using nanoparticles within a hydrogel. Canada Patent No. 2812312C, Canada, Canadian intellectual property office.

Trivedi, D.K., Hollywood, K.A., Rattray, N.J., Ward, H., Trivedi, D.K., Greenwood, J., Ellis, D.I. and Goodacre, R. (2016). Meat, the metabolites: An integrated metabolite profiling and lipidomics approach for the detection of the adulteration of beef with pork. Analyst 141(7): 2155-2164.

Trujillo, E., Davis, C. and Milner, J. (2006). Nutrigenomics, proteomics, metabolomics, and the practice of dietetics. Journal of the American Dietetic Association 106(3): 403-413.

Ullah, H. (2005). Adulterated food: thoughts from an ex-25. Patriate, Daily Star.

Uncu, A.T., Uncu, A.O., Frary, A. and Doganlar, S. (2017). Barcode DNA length polymorphisms vs fatty acid profiling for adulteration detection in olive oil. Food Chemistry 221: 1026-1033.

Van Rijswijk, W. and Frewer, L.J. (2008). Consumer perceptions of food quality and safety and their relation to traceability. British Food Journal 110(10): 1034-1046.

Van Rijswijk, W. and Frewer, L.J. (2012). Consumer needs and requirements for food and ingredient traceability information. International Journal of Consumer Studies 36(3): 282-290.

Venturelli, G.L., Bischoff, J.L., Scariot, M.C., Rossi, G.B. and Arisi, A.C.M. (2019). Applicability of quantitative polymerase chain reaction (qPCR) assays for common bean authentication in processed food. International Journal of Food Science & Technology 54(4): 1381-1389.

Wallace, E.D., Oberlies, N.H., Cech, N.B. and Kellogg, J.J. (2018). Detection of adulteration in Hydrastis canadensis (golden seal) dietary supplements via untargeted mass spectrometry- based metabolomics. Food and Chemical Toxicology 120: 439-447.

Weller, A., Hori, M., Shozugawa, K. and Steinhauser, G. (2018). Rapid ultra-trace determination of Fukushima-derived radionuclides in food. Food Control 85:376-384.

Wu, X., Siehnel, R.J., Garudathri,)., Staudinger, B.J., Hisert, K.B., Ozer, E.A., Hauser, A.R., Eng, J.K., Manoil, C, Singh, RK. and Bruce, J.E. (2019). In vivo proteome of Pseudomonas aeruginosa in airways of cystic fibrosis patients. Journal of Proteome Research 18(6): 2601-2612.

Xanthopoulou, A., Ganopoulos, I., Bosmali, I., Tsaftaris, A. and Madesis, P. (2017). DNA fingerprinting as a novel tool for olive and olive oil authentication, traceability, and detection of functional compounds. Olives and Olive Oil as Functional Foods: Bioactivity, Chemistry and Processing, John Wiley & Sons Ltd, 587-601.

Xing, R.R., Hu, R.R., Han, J.X., Deng, T.T. and Chen, Y. (2020). DNA barcoding and minibarcoding in authenticating processed animal-derived food: A case study involving the Chinese market. Food Chemistry 309:125653.

Xu, L„ Lao, F„ Xu, Z„ Wang, X., Chen, F„ Liao, X., Chen, A. and Yang, S. (2019). Use of liquid chromatography quadrupole time-of-flight mass spectrometry and metabolomic approach to discriminate coffee brewed by different methods. Food Chemistry 286: 106-112.

Xu, Y.J. (2017). Foodomics: A novel approach for food microbiology. TrAC Trends in Analytical Chemistry 96:14-21.

Yi, Y., Tang, C, Yi, T., Yang, Z. and Zhang, S. (2017). Health risk assessment of heavy metals in fish and accumulation patterns in food web in the upper Yangtze River, China. Ecotoxicology and Environmental Safety 145:295-302.

Zio, S., Cisse, H., Zongo, O., Guira, E, Tapsoba, E, Siourime, N., Zongo, C, Traore, Y. and Savadogo, A. (2020). The oils refining process and contaminants in edible oils: A review. Journal of Food Technology 7(1): 9-47.