Concluding Remarks

In this chapter we have discussed the complex role of microRNAs in the pancreatic dysfunction and insulin resistance that contribute to the development of diabetes, as well as their role in the development of microvascular and macrovascular complications, with special focus on cardiac disease and limb ischaemia. The identification of miRNAs involved in these pathological processes is the first step in the approach for finding improved diagnostic and therapeutic tools. The use of miRNA mimics and inhibitors are an attractive strategy for targeted therapy of diabetic vascular complications.

Conflict of Interest The authors declare that they have no conflict of interest.


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