Pancreatic Cancer

Pancreatic cancer presents as an aggressiveness disease, with the later diagnosis and the poor response to chemotherapy or molecular target drugs contributing to the poor prognosis of this cancer. The diagnosis of this disease is commonly made in patients over 70 years. The association of age and resection complication has been investigated and shown that the mortality increases during the first 30 and 90 days after surgery in older patients. However, among the patients that survived after this period the overall survival after 90 days is similar to the younger patients [38].

Lung Cancer

Non-small cell lung cancer: Older patients with NSCLC may tolerate surgical resection. Adjuvant therapy in patients with ECOG 0-1 has the same advantages for older compared to young patients. The same is observed in advanced disease. However, the addition of bevacizumab to the chemotherapy has not been associated to a better quality of life [39].

Small cell lung cancer: The treatment of this cancer with cisplatin and etoposide had the same response in older patients as that observed in younger patients. Carboplatin had the same effects as cisplatin with a decrease in renal toxicity but a higher hematological toxicity [19].

 
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