Ovarian Cancer

Older patients with ovarian cancer used to be treated with less aggressive treatment. The double treatment-surgery and chemotherapy—are not commonly used in this population as they result in poor survival compared to younger patients (18 % versus 53 %) [55, 56]. Peritoneal chemotherapy maybe indicated in some patients over 70 years but increased toxicity and reduced quality of life during treatment should be considered [57].

In conclusion, curative treatments cannot be denied to older patients based only on chronological age. The Comprehensive Geriatric Assessment and other forms of assessment must be used to determine the most appropriate treatment plan according to the functional status, social support and predicted life expectancy. Some older individuals may benefit from aggressive therapies, but they have a higher toxicity and may require a more complex clinical support. The estimated risk of severe toxicity with chemotherapy is only one aspect of treatment planning in the older patient and should be integrated into a multidisciplinary decision.

 
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