Future trends/conclusions

The rapid development of techniques for assessing gene expression has exponentially expanded our knowledge of cell response at the molecular level, allowing identification of how cells regulate specific processes and behaviors. With the increasing use of biomaterials in medicine, understanding how cells respond to foreign materials from a molecular standpoint will be instrumental in development of more appropriate materials. As highlighted within this chapter, utilizing gene expression properly can be a challenging task, particularly in vivo, and the relevance of the data by itself must always be questioned. However, it is clear that gene expression technology will play a pivotal role in future years in the development of rational biomaterials for specific medical applications.

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