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Electrospun Nanofibers Applications in Dentistry

Electrospinning is an excellent technique for fabricating tissue engineering scaffolds in dentistry. A variety of materials including natural polymers (silk, collagen, chitosan), synthetic polymers (PVA, polydioxanone), and nanocomposites (HAp blends) have been electrospun for tissue engineering of oral and dental tissues, i.e., pulp dentin complex, guided tissue regeneration for periodontium, caries prevention, modification of resin composites, implant surface modification, and cartilage regeneration. The major advantage ofelectrospinning is its ability to produce complex geometry ofnanofibrous scaffolds that can be used for dentin-pulp complex regeneration. The goal ofdentin-pulp complex regeneration is to restore the mechanical and physical attributes of the tooth structure. Electrospun NF has been of interest for the repair of defects in periodontal tissues such as alveolar bone, periodontal ligament, and cementum. Biodegradable polymers such as collagen, PLGA, PLA, and PCL possess the disadvantage of poor porosity, surface alignment, and lack of biological functionality. To overcome these drawbacks, significant research has been conducted on electrospun NF, which provides enhanced porosity, cell attachment, and fiber alignment to use in periodontal regeneration. Although electrospinning has added exciting new prospects in the field of periodontal tissue regeneration, much work is needed to validate the application of electrospun nanofibrous scaffolds in the clinical stage with respect to mechanical and biological properties as well as the underlying mechanisms [75].

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Electrospun Nanofibers Application in Ocular Injuries
Injured or damaged corneal epithelium represents one ofthe frequent causes ofimpaired vision or even blindness. Ocular injuries require immediate management that may allow critical function restoration and minimize tissue loss. Such processes may be appropriate for ocular repair dressing, cleansing solutions,...
(Emerging nanotechnologies for diagnostics, drug delivery and medical devices)
Electrospun Nanofibers in Drug Delivery: Fabrication, Advances, and Biomedical Applications
Vibhuti Agraharia, Vivek Agraharia, Jianing Menga, Ashim K. Mitra University of Missouri—Kansas City, Kansas City, MO, United States Contents 1. Introduction 190 1.1 Process of Electrospinning 190 1.2 Parameters Influencing the Electrospinning Process and Fiber Characteristics 191 1.2.1...
(Emerging nanotechnologies for diagnostics, drug delivery and medical devices)
APPLICATIONS OF ELECTROSPUN NANOFIBERS
Electrospun Nanofibers in Tissue Engineering A wide variety ofmethods have been reported in the literature for the fabrication oftissue engineering scaffolds [47]. Electrospun NF scaffolds have exhibited an excellent cell growing capability. Biocompatible and biodegradable NFs are generally preferred...
(Emerging nanotechnologies for diagnostics, drug delivery and medical devices)
Electrospun Nanofibers in Biomedical Application
Electrospun NF scaffolds possess properties of interconnection between pores and cell adhesion, infiltration, migration, and proliferation, while permitting free exchange of cell nutrients and wastes in addition to a high surface-to-volume ratio. Other characteristics of the electrospun NF include surface...
(Emerging nanotechnologies for diagnostics, drug delivery and medical devices)
Composite Electrospun Nanofibers for Energy Scavenging Applications
Electrospun nanocomposites are promising materials in terms of energy harvesting or scavenging applications. Electrospinning encompasses tuning of many optimized parameters, like fiber diameter and alignment of polymer chains as well as incorporated fillers, influencing the output voltage of self-powered...
(Nanotechnology in Textiles: Advances and Developments in Polymer Nanocomposites)
Electrospun Nanofibers in Tissue Engineering
A wide variety ofmethods have been reported in the literature for the fabrication oftissue engineering scaffolds [47]. Electrospun NF scaffolds have exhibited an excellent cell growing capability. Biocompatible and biodegradable NFs are generally preferred over conventional scaffolds because of their...
(Emerging nanotechnologies for diagnostics, drug delivery and medical devices)
Electrospun Nanofibers in Drug Delivery
The aim of designing an electrospun NFs in drug delivery system is to control drug release over a definite period depending on medical conditions [79]. The rate of drug release can be tailored on the basis of fiber diameter, porosity, and drug-binding mechanisms for various applications. To date, a large...
(Emerging nanotechnologies for diagnostics, drug delivery and medical devices)
Electrospun Nanofibers
The major problem associated with carbon nanombes for immobilization is mass transfer limitation and difficulty in recycling due to good dispersion (Wang et al. 2009). Electrospun nanofibers have more potential to avoid these above-mentioned problems (Nakane et al. 2007). Lipases were attached to the...
(Nanobiotechnology for Sustainable Bioenergy and Biofuel Production)
STIMULI-RESPONSIVE NANOFIBERS IN DRUG DELIVERY APPLICATIONS
A stimuli-responsive nanocarrier provides a smart system for various therapeutic applications [15]. Generally, stimuli-responsive systems are able to enhance/trigger the release of therapeutic drugs in response to triggering signals (intrinsic or extrinsic). The intrinsic signals include pH, temperature,...
(Emerging nanotechnologies for diagnostics, drug delivery and medical devices)