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Electrospun Nanofibers in Biomedical Application

Electrospun NF scaffolds possess properties of interconnection between pores and cell adhesion, infiltration, migration, and proliferation, while permitting free exchange of cell nutrients and wastes in addition to a high surface-to-volume ratio. Other characteristics of the electrospun NF include surface modification of bioactive molecules, cell recognizable ligands, and the ability of imitating natural ECM in addition to the mechanical strength, biocompatibility, and biodegradability. Electrospun NF shows remarkable application in drug delivery, wound dressing, medical implants, biosensors, and dental surgery (as discussed earlier). Electrospun NF offers a cost-effective method to mimic native ECM composed of an interlocking meshwork of proteins and glycosaminoglycans. Other important raw materials include PCL, PLA, PGA, PLGA, and PLCL. These copolymers are very suitable because of their ease of processing, mechanical properties, and biocompatibility. Natural polymers, such as collagen, gelatin, chitosan, and silk fibroin, have also been electrospun into NF scaffolds for biomedical applications [86].

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Electrospun Nanofibers in Drug Delivery: Fabrication, Advances, and Biomedical Applications
Vibhuti Agraharia, Vivek Agraharia, Jianing Menga, Ashim K. Mitra University of Missouri—Kansas City, Kansas City, MO, United States Contents 1. Introduction 190 1.1 Process of Electrospinning 190 1.2 Parameters Influencing the Electrospinning Process and Fiber Characteristics 191 1.2.1...
(Emerging nanotechnologies for diagnostics, drug delivery and medical devices)
APPLICATIONS OF ELECTROSPUN NANOFIBERS
Electrospun Nanofibers in Tissue Engineering A wide variety ofmethods have been reported in the literature for the fabrication oftissue engineering scaffolds [47]. Electrospun NF scaffolds have exhibited an excellent cell growing capability. Biocompatible and biodegradable NFs are generally preferred...
(Emerging nanotechnologies for diagnostics, drug delivery and medical devices)
Electrospun Nanofibers Applications in Dentistry
Electrospinning is an excellent technique for fabricating tissue engineering scaffolds in dentistry. A variety of materials including natural polymers (silk, collagen, chitosan), synthetic polymers (PVA, polydioxanone), and nanocomposites (HAp blends) have been electrospun for tissue engineering of oral...
(Emerging nanotechnologies for diagnostics, drug delivery and medical devices)
Electrospun Nanofibers Application in Ocular Injuries
Injured or damaged corneal epithelium represents one ofthe frequent causes ofimpaired vision or even blindness. Ocular injuries require immediate management that may allow critical function restoration and minimize tissue loss. Such processes may be appropriate for ocular repair dressing, cleansing solutions,...
(Emerging nanotechnologies for diagnostics, drug delivery and medical devices)
Composite Electrospun Nanofibers for Energy Scavenging Applications
Electrospun nanocomposites are promising materials in terms of energy harvesting or scavenging applications. Electrospinning encompasses tuning of many optimized parameters, like fiber diameter and alignment of polymer chains as well as incorporated fillers, influencing the output voltage of self-powered...
(Nanotechnology in Textiles: Advances and Developments in Polymer Nanocomposites)
TiO2 Layers on Ti and Ti Alloys for Biomedical Applications
TiO2 layers on Ti and Ti alloys are reported to be effective for improving biological performance such as biomimetic growth of apatite [14], initial adhesion of osteoblast-like cells [15], bone-bonding ability [16], and bone growth [17]; in fact, Ti implants coated with a porous TiO2 layer through anodic...
(Interface Oral Health Science 2014)
Biomedical Applications: Fiber or Tube Reinforced Scaffolds for Hard Tissue
Dental Applications of the Scaffolds Reinforced by Fibers or Tubes Tooth of human being are highly calcified and the hardest tissues in the body. However, the diseases of the tooth can be seen in all ages and their prevalence rate is high [52]. In the last few decades, dentistry has developed...
(Tissue Repair : Reinforced Scaffolds)
Biomedical Applications: Fiber or Tube Reinforced Scaffolds for Soft Tissue
Cartilage Tissue Cartilage, composed of chondrocytes, fibers and matrix, is a slightly resilient tough tissue with the functions of support and protection in the body. As a typical cartilage tissue, articular cartilage is smooth and elastic and has the function of maximizing absorption and buffer...
(Tissue Repair : Reinforced Scaffolds)
BIOMEDICAL APPLICATIONS
Orthopedic devices Besides aerospace applications, a significant amount of research into SMPs has been focused on biomedical applications. While initial research often shows great promise, the successful commercialization and clinical application of such devices did not start until 2009. MedShape,...
(Shape-Memory Polymer Device Design. A volume in Plastics Design Library)