Treatment

I am bitterly disappointed because I have lost weight and reduced my salt intake, but I have been told that my blood pressure is still raised. What should I do?

You will need medication. Lowering your blood pressure to normal removes your chances of having a stroke and protects your heart, brain and kidneys from damage.

The good news is that treatment is very effective. Controlling high blood pressure helps prevent all the problems developing and restores you to a normal life expectancy. We now have many effective medications available to treat hypertension that need to be taken only

Table 2.2 Common drugs for raised blood pressure

Generic (real) name

Trade name

(can vary in different countries)

Diuretics

bendroflumethiazide (bendrofluazide) Aprinox, Neo-NaClex

chlortalidone (chlorthalidone)

Hygroton

hydrochlorothiazide

Hydrenox, Hydrosaluric

indapamide

Natrilix

Potassium-sparing diuretics

amiloride

Usually in combination

triamterine

Dytac

spironolactone

Aldactone

Beta-blockers

acebutolol

Sectral

atenolol

Tenormin

bisoprolol

Emcor, Cardicor

carvedilol

Eucardic

celiprolol

Celectol

labetalol

Trandate

metoprolol

Betaloc, Lopresor

nebivolol

Nebilet

pindolol

Visken

propranolol

Beta-Prograne, Inderal

timolol

Betim

Calcium antagonists

amlodipine

Istin

diltiazem

Tildiem, Adizem, Dilzem

felodipine

Plendil

isradipine

Prescal

lacidipine

Motens

lercanidipine

Zanidip

nicardipine

Cardene SR

nifedipine

Adalat, Adalat LA, Cardilate MR,

Coracten XL,

nisoldipine

Syscor MR

verapamil

Securon, Cordilox, Univer

ACE inhibitors

captopril

Capoten, Acepril

cilazapril

Vascace

enalapril

Innovace

fosinopril

Staril

lisinopril

Carace, Zestril

moexipril

Perdix

perindopril

Coversyl

quinapril

Accupro

ramipril

Tritace

trandolapril

Gopten

Alpha-blockers

doxazosin

Cardura

indoramin

Baratol

prazosin

Hypovase

terazosin

Hytrin

Angiotensin II antagonists

candesartan

Amias

irbesartan

Aprovel

losartan

Cozaar

olmesartan

Olmetec

telmisartan

Micardis

valsartan

Diovan

Combination products

atenolol + chlorthalidone

Tenoret 50, Tenoretic

atenolol + nifedipine

Tenif, Beta-Adalat

captopril + hydrochlorothiazide

Capozide, Acezide

enalapril + hydrochlorothiazide

Innozide

lisinopril + hydrochlorothiazide

Zestoretic

losartan + hydrochlorothiazide

Cozaar-Comp

metoprolol + hydrochlorothiazide

Co-Betaloc

propranolol + bendrofluazide

Inderetic

perindopril + indapamide

Coversyl Plus

irbesartan + hydrochlorothiazide

Co Aprovel

valsartan + amlodipine

Exforge

Table 2.3 Blood pressure-lowering drugs and their possible side effects

Drug type

Possible side effects

Beta-blockers

Cold hands and feet with or without

numb feeling (pins and needles);

lethargy, poor concentration; heavy

legs (like a zombie); wheezing; dry eyes;

vivid dreams

Diuretics

Impotence; rashes; gout; possible

problems for people with diabetes;

muscle cramps; spironolactone: swollen

or painful breasts

Calcium antagonists

Flushing, headaches and dizziness;

swollen ankles which may be painful;

bloated feeling and constipation

ACE inhibitors

Dry hacking cough; rash; stomach

upsets

Alpha-blockers

Tiredness; dizziness; dry mouth

Angiotensin II antagonists

No major or common ones reported

Drugs that act on the brain

Weakness, drowsiness, dizziness on

(e.g. methyldopa,

standing; dry mouth; depression;

moxonidine)

impotence

once a day; if one causes a side effect, there is no need to despair because we have lots of choices and we can always find another drug that lowers the pressure to suit you.

 
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