Nicotine Nasal Spray

Table of Contents:

Nicotine nasal spray comes as a liquid to spray into the nose. It should be used along with a smoking cessation program, which may include a support group, counseling, or specific cognitive or behavioral techniques. It allows smokers to cut back on their intake of nicotine gradually. Nicotine is absorbed rapidly through the nasal membranes. To use the nasal spray, follow these steps:

Wash your hands.

Gently blow your nose to clear your nasal passages.

Remove the cap of the nasal spray by pressing in the circles on the side of the bottle.

To prime the pump before the first use, hold the bottle in front of a tissue or paper towel.

Pump the spray bottle six to eight times until a fine spray appears. Throw away the tissue or towel.

Tilt your head back slightly.

Insert the tip of the bottle as far as you comfortably can into one nostril, pointing the tip toward the back of your nose. Breathe through your mouth.

Pump the spray firmly and quickly one time. Do not sniff, swallow, or inhale while spraying. If your nose runs, gently sniff to keep the nasal spray in your nose. Wait two or three minutes before blowing your nose.

Repeat steps six to eight for the second nostril. Replace the cover on the spray bottle.

If you have not stopped smoking at the end of four weeks, talk with your doctor. Your doctor can try to help you understand why you were not able to stop smoking and make plans to try again. Ask your pharmacist or doctor for a copy of the manufacturer's information for the patient. Stay in touch with your doctor. He or she may need to change the doses of your medications once you stop smoking completely. If you continue smoking while using the nicotine nasal spray, you may have some adverse effects. Remember a nicotine overdose can be lethal.

Other Instructions:

• Handle the bottle with care. If the bottle drops, it may break. If this happens, wear rubber gloves and clean up the spill immediately with a cloth or paper towel. Avoid touching the liquid. Throw away the used cloth or paper towel in the trash. Pick up the broken glass carefully using a broom. Wash the area of the spill a few times.

• If even a small amount of nicotine solution comes in contact with the skin, lips, mouth, eyes, or ears, these areas should be immediately rinsed with water.

Nicotine Inhaler

The inhaler should be used with a smoking cessation program, which may include support groups, counseling, or specific cognitive and behavioral therapies. Nicotine oral inhalation comes as a cartridge to inhale by mouth using a special inhaler.

Directions: It is very important you follow the directions on your prescription label carefully and exactly as directed.

Your doctor may increase or decrease your dose depending on your urge to smoke. The inhaler has a plastic mouthpiece with a nicotine plug to deliver the nicotine to the mucous membranes of the mouth. The nicotine in the cartridges is released by frequent puffing over 20 minutes. You may use up a cartridge all at once or puff on it for a few minutes at a time until the nicotine is finished. Try different schedules to see what works best for you.

Read the directions for how to use the inhaler and ask your doctor or pharmacist to show you the proper technique. Practice using the inhaler while in his or her presence. If you continue smoking while using nicotine inhalation, you may experience adverse side effects. Remember: an overdose of nicotine kills. You should know that even though you are using nicotine inhalation, you may have some withdrawal symptoms.

Nicotine Lozenge

This is a more recent addition to the growing number of tools to combat nicotine withdrawal symptoms. Slowly allow the lozenge to melt in your mouth.


For weeks one to six of treatment, you should use one lozenge every one to two hours. Use at least nine lozenges per day to increase your chances of quitting. During weeks seven to nine, you should use one lozenge every two to four hours. Weeks 10 to 12, you should use one lozenge every four to eight hours. Do not use more than five lozenges in six hours or more than 20 lozenges per day. Do not use more than one lozenge at a time or use one lozenge right after another. Using too many lozenges at a time or one after another can cause side effects such as hiccups, heartburn, and nausea. Do not eat while the lozenge is in your mouth.

Stop using the nicotine lozenges after 12 weeks. After 12 weeks if you still feel the need to use nicotine lozenges, talk to your doctor.

Table 9 summarizes the NRTs presented.

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There is compelling evidence that medication aids in abstinence.

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