Differentiating between specific dementias may influence clinical decision making regarding prognosis and therapy. Although fewer resources have been dedicated to the investigation of less common dementias compared to Alzheimer disease, there have still been significant advances in
Fig. 5.8 Comparison of frontotemporal dementia (FTD) and Alzheimer disease (AD). Significance maps of systematic brain abnormalities in FTD and AD patients relative to control subjects (CN) (AD
appreciating white matter disruption in a variety of dementia conditions.