Menu
Home
Log in / Register
 
Home arrow Environment arrow Inflammatory Disorders of the Nervous System: Pathogenesis, Immunology, and Clinical Management
Source

Clinical Classification

The Myasthenia Gravis Foundation of America (MGFA) clinical classification divides MG into five main classes and several subclasses [26]. It is designed to identify subgroups of patients with MG who share distinct clinical features or severity of disease that may indicate different prognoses or responses to therapy. It should not be used to measure outcome and is as follows:

Class I MG is characterized by the following:

  • 1. Any ocular muscle weakness.
  • 2. May have weakness of eye closure.
  • 3. All other muscle strengths are normal.

Class II MG is characterized by the following:

  • 1. Mild weakness affecting muscles other than ocular muscles
  • 2. May also have ocular muscle weakness of any severity

Class IIa MG is characterized by the following:

  • 1. Predominantly affecting limb muscles, axial muscles, or both
  • 2. May also have lesser involvement of oropharyngeal muscles

Class IIb MG is characterized by the following:

  • 1. Predominantly affecting oropharyngeal muscles, respiratory muscles, or both
  • 2. May also have lesser or equal involvement of limb muscles, axial muscles, or both

Class III MG is characterized by the following:

  • 1. Moderate weakness affecting muscles other than ocular muscles
  • 2. May also have ocular muscle weakness of any severity

Class IIIa MG is characterized by the following:

  • 1. Predominantly affecting limb muscles, axial muscles, or both
  • 2. May also have lesser involvement of oropharyngeal muscles

Class IIIb MG is characterized by the following:

  • 1. Predominantly affecting oropharyngeal muscles, respiratory muscles, or both
  • 2. May also have lesser or equal involvement of limb muscles, axial muscles, or both

Class IV MG is characterized by the following:

  • 1. Severe weakness affecting muscles other than ocular muscles
  • 2. May also have ocular muscle weakness of any severity

Class IVa MG is characterized by the following:

  • 1. Predominantly affecting limb muscles, axial muscles, or both
  • 2. May also have lesser involvement of oropharyngeal muscles

Class IVb MG is characterized by the following:

  • 1. Predominantly affecting oropharyngeal muscles, respiratory muscles, or both
  • 2. May also have lesser or equal involvement of limb muscles, axial muscles, or both

Class V MG is characterized by the following:

  • 1. Intubation with or without mechanical ventilation, except when employed during routine postoperative management.
  • 2. The use of feeding tube without intubation places the patient in class IVb [2, 13].
 
Source
Found a mistake? Please highlight the word and press Shift + Enter  
< Prev   CONTENTS   Next >
 
Subjects
Accounting
Business & Finance
Communication
Computer Science
Economics
Education
Engineering
Environment
Geography
Health
History
Language & Literature
Law
Management
Marketing
Mathematics
Political science
Philosophy
Psychology
Religion
Sociology
Travel