Menu
Home
Log in / Register
 
Home arrow Environment arrow Inflammatory Disorders of the Nervous System: Pathogenesis, Immunology, and Clinical Management
Source

The Venous Connection: The Role of Veins in Neurodegenerative Disease

Clive Beggs

Context

The cerebral venous drainage system has often been viewed simply as a series of collecting vessels passively channelling blood from the brain back to the heart. However, recent studies suggest that this system may be far from passive and that in fact it plays an important role in regulating intracranial pressure (ICP) [1], the stiffness of the brain parenchyma [2] and the dynamics of the cerebrospinal fluid (CSF) in the cranium [3]. Anomalies of the cervical veins have also been reportedly linked with several neurologic conditions, including multiple sclerosis (MS) [4-6], Parkinson’s disease [7], Meniere’s disease [8, 9] and Alzheimer’s disease [10, 11]. As such, this raises intriguing questions as to whether or not changes in the cerebral venous drainage system can alter the biomechanics of the intracranial space, resulting in neurodegeneration. In this review we investigate this issue and explore the connection between veins and neurologic disease.

 
Source
Found a mistake? Please highlight the word and press Shift + Enter  
< Prev   CONTENTS   Next >
 
Subjects
Accounting
Business & Finance
Communication
Computer Science
Economics
Education
Engineering
Environment
Geography
Health
History
Language & Literature
Law
Management
Marketing
Mathematics
Political science
Philosophy
Psychology
Religion
Sociology
Travel