Herbal Traditional Medicines

  • Case Study Example 5.
  • - Using herbal and traditional medicine resources (listed below), select either a single herb or combination of herbs (as in a recipe)
  • - discuss the potential treatment of a condition and/or disease
  • - list the relevant phytochemicals
  • - determine if the targeted phytochemicals have potential positive effect on the condition
  • - show a gene-target interaction diagram
  • • Resources
  • - KEGG Environ43
  • - Traditional Chinese Medicine Integrated Database: TCMID44
  • - TCMgeneDIT:45 TCMs, genes, diseases, effects, and ingredients
  • - Traditional Chinese Medicine Database@Taiwan46
  • - Natural Center for Complementary and Alternative Medicines (NCCAM): herbs at a glance47
  • - Medline Plus: herbs and supplements48
  • - Traditional Chinese Medicine Systems Pharmacology Database (TCMSP) and analysis platform49
  • Case Study Example 6.
  • • Using an example from case study 5 suggest a drug-herb interaction

that may involve drug metabolism or individual differences in response

• Show the potential interaction in pathway form and discuss whether

this is a known interaction or hypothesized from your work

  • Environmental Chemicals and Health Relationships
  • Case Study Example 7. A current topic is selected that recently appeared in the scientific literature or the news media. This topic changes each year. The following is an example.

NBC News recently did an investigative report on the safety of our children’s playgrounds and sports fields. For more than 5 years now, there have been a slew of studies looking to see if there is a link between the rise of cancer cases among athletes and the surfaces they play on.50 Artificial turf fields can be found all over the United States as the popular alternative to natural grass fields which require a lot more upkeep; however, the chemicals involved in making the turf has been drawing some concem.51,5Z

Of the most concern is artificial grass that uses infill called crumb rubber made of pieces of old tires. This is what makes these fields more bouncy, protecting players better from more serious injuries like concussions. The downside is that when players’ bodies connect with the field, little pieces of the infill fly up and scatter everywhere. After a game or practice, players will find these crumbs not only in their uniforms, but in their hair and inside cuts and abrasions they received on the field. For soccer goalies however, with their full body dives to the ground, these crumbs can also get in their mouths during play.

Because different types of tires made from a large variety of materials are used to make the turf, it is hard to pinpoint the particular chemicals that could be causing the increase in cancer rates. The EPA lists mercury, lead, benzene and arsenic as well as other chemicals and carcinogens as being the ingredients in tires.

  • • You are asked to comment scientifically about this issue offering an informed opinion
  • • Discuss what you know about this issue
  • • Discuss what you need to know to form the informed opinion
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